Research workbench
Human ubiquitin-conjugating enzyme E2 J2
Analyse Human ubiquitin-conjugating enzyme E2 J2 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2F4W
- Type
- protein
- Length
- 299 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ubiquitin-conjugating enzyme E2, J2
- EC
- 6.3.2.19
- Pockets
- 2 · best druggability 0.29
Structure
x-ray diffraction · 2 distinct chains · 38% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Ubiquitin-conjugating enzyme E2, J2 (EC 6.3.2.19) | protein | 147 | 38% helix, 20% strand | — |
| B | Ubiquitin-conjugating enzyme E2, J2 (EC 6.3.2.19) | protein | 152 | 39% helix, 20% strand | — |
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 57 | 0.29 | 0.74 | 15 | empty |
| 2 | 54 | 0.27 | 0.73 | 12 | empty |
Interfaces
1 interface between chains.
- A–B · 114 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 2F4W · Human ubiquitin-conjugating enzyme E2 J2 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 2F4W · PDBe 2F4W
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.