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Crystal structure of grea factor homolog 1 (GFH1) protein of thermus thermophilus

Analyse Crystal structure of grea factor homolog 1 (GFH1) protein of thermus… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2F23
Type: protein
Length: 308 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Anti-cleavage anti-grea transcription factor GFH1
UniProt: Q72JT8
Pockets: 1 · best druggability 0.69

Structure

x-ray diffraction · 1 distinct chain · 42% helix, 26% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Anti-cleavage anti-grea transcription factor GFH1	protein	154	42% helix, 26% strand	Q72JT8

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	527	0.69	0.79	53	empty

Interfaces

1 interface between chains.

A–B · 961 Å² buried · 23 hydrogen bonds · protein-protein

Compared structures

2F23 · Crystal structure of GreA factor homolog 1 (Gfh1) protein of Thermus thermophilus · the same entry in another collection · chain A against A, TM-score 1.00
Q72JT8 · AlphaFold monomer V2.0 prediction for transcription inhibitor protein GFH1 (Q72JT8) · a predicted model of the same protein · chain A against A, TM-score 0.60

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q72JT8
Elsewhere: RCSB PDB 2F23 · PDBe 2F23 · UniProt Q72JT8

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