Research workbench
X-ray crystal structure of protein BT_1218 from bacteroides thetaiotaomicron. northeast structural genomics consortium target BTR8.
Analyse X-ray crystal structure of protein BT_1218 from bacteroides thetaiotaomicron.… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2F20
- Type
- protein
- Length
- 465 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Conserved hypothetical protein, with conserved domain
- UniProt
- Q8A8E9
- Pockets
- 4 · best druggability 0.79
Structure
x-ray diffraction · 2 distinct chains · 28% helix, 35% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Conserved hypothetical protein, with conserved domain | protein | 233 | 29% helix, 35% strand | Q8A8E9 |
| B | Conserved hypothetical protein, with conserved domain | protein | 232 | 28% helix, 35% strand | Q8A8E9 |
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 688 | 0.79 | 0.84 | 58 | empty |
| 2 | 85 | 0.34 | 0.75 | 18 | empty |
| 3 | 82 | 0.31 | 0.73 | 17 | empty |
| 4 | 62 | 0.30 | 0.75 | 16 | empty |
Interfaces
1 interface between chains.
- A–B · 894 Ų buried · 14 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 12 modified (engineered).
Compared structures
- 2F20 · X-ray Crystal Structure of Protein BT_1218 from Bacteroides thetaiotaomicron. Northeast… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q8A8E9
- Elsewhere: RCSB PDB 2F20 · PDBe 2F20 · UniProt Q8A8E9
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