Research workbench
Structural study of project id ST1242 from sulfolobus tokodaii STRAIN7
Analyse Structural study of project id ST1242 from sulfolobus tokodaii STRAIN7 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2EP5
- Type
- protein
- Length
- 1,395 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- 350AA long hypothetical aspartate-semialdehyde dehydrogenase
- EC
- 1.2.1.11
- UniProt
- Q971Y6
- Pockets
- 12 · best druggability 0.78
Structure
x-ray diffraction · 2 distinct chains · 37% helix, 23% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C | 350AA long hypothetical aspartate-semialdehyde dehydrogenase (EC 1.2.1.11) | protein | 349 | 37% helix, 23% strand | Q971Y6 |
| D | 350AA long hypothetical aspartate-semialdehyde dehydrogenase (EC 1.2.1.11) | protein | 348 | 37% helix, 23% strand | Q971Y6 |
Pockets
12 pockets found on a 1 Å grid, 7 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1042 | 0.78 | 0.80 | 78 | empty |
| 2 | 934 | 0.74 | 0.78 | 89 | empty |
| 3 | 52 | 0.70 | 0.97 | 16 | empty |
| 4 | 272 | 0.63 | 0.81 | 41 | empty |
| 5 | 319 | 0.63 | 0.80 | 36 | empty |
Interfaces
6 interfaces between chains.
- C–D · 1675 Ų buried · 20 hydrogen bonds · protein-protein
- A–B · 1635 Ų buried · 27 hydrogen bonds · protein-protein
- A–C · 694 Ų buried · 14 hydrogen bonds · protein-protein
- B–D · 687 Ų buried · 14 hydrogen bonds · protein-protein
- B–C · 292 Ų buried · 2 hydrogen bonds · protein-protein
Compared structures
- 2EP5 · Structural study of Project ID ST1242 from Sulfolobus tokodaii strain7 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q971Y6
- Elsewhere: RCSB PDB 2EP5 · PDBe 2EP5 · UniProt Q971Y6
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