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Solution structure of the fifth ig-like domain from human roundabout HOMO1

Analyse Solution structure of the fifth ig-like domain from human roundabout HOMO1 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2EO9
Type: protein
Length: 118 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Roundabout homolog 1
UniProt: Q9Y6N7
Pockets: 1 · best druggability 0.33

Structure

solution nmr · 1 distinct chain · 3% helix, 36% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Roundabout homolog 1	protein	118	3% helix, 36% strand	Q9Y6N7

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	52	0.33	0.78	13	empty

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

2EO9 · Solution structure of the fifth ig-like domain from human Roundabout homo1 · the same entry in another collection · chain A against A, TM-score 1.00
Q9Y6N7 · AlphaFold monomer V2.0 prediction for roundabout homolog 1 (Q9Y6N7) · a predicted model of the same protein · chain A against A, TM-score 0.75

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9Y6N7
Elsewhere: RCSB PDB 2EO9 · PDBe 2EO9 · UniProt Q9Y6N7

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