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Solution structure of the insertion region (510-573) of fthfs domain from mouse methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like protein

Analyse Solution structure of the insertion region (510-573) of fthfs domain from mouse… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2EO2
Type: protein
Length: 71 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Adult male hypothalamus cdna, riken full-length enriched library, CLONE:A230045M11…
UniProt: Q8CAL0
Pockets: 1 · best druggability 0.38

Structure

solution nmr · 1 distinct chain · 38% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Adult male hypothalamus cdna, riken full-length enriched library, CLONE:A230045M11 PRODUCT:WEAKLY similar to C1- tetrahydrofolate synthase	protein	71	38% helix, 0% strand	Q8CAL0

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	86	0.38	0.77	13	empty

Compared structures

2EO2 · Solution structure of the insertion region (510-573) of FTHFS domain from mouse… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8CAL0
Elsewhere: RCSB PDB 2EO2 · PDBe 2EO2 · UniProt Q8CAL0

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