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Structural study of project id TTHB049 from thermus thermophilus HB8 (L52M)

Analyse Structural study of project id TTHB049 from thermus thermophilus HB8 (L52M) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2EKZ
Type: protein
Length: 341 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Alpha-ribazole-5'-phosphate phosphatase
UniProt: Q53WB3
Pockets: 5 · best druggability 0.70

Structure

x-ray diffraction · 2 distinct chains · 38% helix, 17% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Alpha-ribazole-5'-phosphate phosphatase	protein	171	37% helix, 17% strand	Q53WB3
B	Alpha-ribazole-5'-phosphate phosphatase	protein	170	39% helix, 17% strand	Q53WB3

Pockets

5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	362	0.70	0.82	39	empty
2	289	0.67	0.82	30	empty
3	58	0.49	0.86	23	empty
4	76	0.48	0.83	18	empty
5	71	0.30	0.73	16	empty

Interfaces

1 interface between chains.

A–B · 736 Å² buried · 11 hydrogen bonds · protein-protein

Compared structures

2EKZ · Structural study of Project ID TTHB049 from Thermus thermophilus HB8 (L52M) · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q53WB3
Elsewhere: RCSB PDB 2EKZ · PDBe 2EKZ · UniProt Q53WB3

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