Research workbench
Conserved hypothetical proteim (TTHB059) from thermo thermophilus HB8
Analyse Conserved hypothetical proteim (TTHB059) from thermo thermophilus HB8 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2EHW
- Type
- protein
- Length
- 463 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Hypothetical protein TTHB059
- UniProt
- Q53WA3
- Pockets
- 7 · best druggability 0.76
Structure
x-ray diffraction · 3 distinct chains · 79% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Hypothetical protein TTHB059 | protein | 115 | 82% helix, 0% strand | Q53WA3 |
| C | Hypothetical protein TTHB059 | protein | 117 | 76% helix, 0% strand | Q53WA3 |
| D | Hypothetical protein TTHB059 | protein | 116 | 80% helix, 0% strand | Q53WA3 |
Pockets
7 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1013 | 0.76 | 0.79 | 70 | empty |
| 2 | 82 | 0.33 | 0.74 | 13 | empty |
| 3 | 65 | 0.33 | 0.76 | 13 | empty |
| 4 | 63 | 0.29 | 0.74 | 11 | empty |
| 5 | 66 | 0.29 | 0.73 | 8 | empty |
Interfaces
5 interfaces between chains.
- C–D · 736 Ų buried · 12 hydrogen bonds · protein-protein
- A–B · 732 Ų buried · 7 hydrogen bonds · protein-protein
- A–C · 267 Ų buried · 0 hydrogen bonds · protein-protein
- B–D · 85 Ų buried · 0 hydrogen bonds · protein-protein
- B–C · 63 Ų buried · 3 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 5 modified (engineered).
Compared structures
- 2EHW · Conserved hypothetical proteim (TTHB059) from Thermo thermophilus HB8 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q53WA3
- Elsewhere: RCSB PDB 2EHW · PDBe 2EHW · UniProt Q53WA3
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.