Research workbench
Crystal structure of acetylornithine aminotransferase from thermotoga maritima
Analyse Crystal structure of acetylornithine aminotransferase from thermotoga maritima in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2E54
- Type
- protein
- Length
- 385 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Acetylornithine aminotransferase
- EC
- 2.6.1.11
- UniProt
- Q9X2A5
- Ligands
- PLP, NA
- Pockets
- 2 · best druggability 0.60
Structure
x-ray diffraction · 1 distinct chain · 38% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Acetylornithine aminotransferase (EC 2.6.1.11) | protein | 385 | 38% helix, 20% strand | Q9X2A5 |
Ligands and binding sites
- PLP · Pyridoxal-5'-phosphate · ligand · chains A
- NA · Sodium ion · metal · 2 copies · chains A
- EDO · 1,2-ethanediol · additive · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 423 | 0.60 | 0.75 | 53 | PLP |
| 2 | 196 | 0.49 | 0.75 | 29 | empty |
Compared structures
- 2E54 · Crystal structure of acetylornithine aminotransferase from Thermotoga maritima · the same entry in another collection · chain A against A, TM-score 1.00
- Q9X2A5 · AlphaFold monomer V2.0 prediction for acetylornithine aminotransferase (Q9X2A5) · a predicted model of the same protein · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9X2A5
- Elsewhere: RCSB PDB 2E54 · PDBe 2E54 · UniProt Q9X2A5
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