Research workbench
Crystal structure of hemagglutinin subcomponent complex (ha- 33/HA-17) from clostridium botulinum serotype D strain 4947
Analyse Crystal structure of hemagglutinin subcomponent complex (ha- 33/HA-17) from… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2E4M
- Type
- protein
- Length
- 713 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Main hemagglutinin component; Ha-17
- UniProt
- P46084, Q9LBR4
- Pockets
- 4 · best druggability 0.66
Structure
x-ray diffraction · 2 distinct chains · 8% helix, 47% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Main hemagglutinin component | protein | 285 | 9% helix, 46% strand | P46084 |
| C | Ha-17 | protein | 143 | 4% helix, 50% strand | Q9LBR4 |
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 554 | 0.66 | 0.77 | 69 | empty |
| 2 | 145 | 0.41 | 0.75 | 28 | empty |
| 3 | 122 | 0.37 | 0.73 | 28 | empty |
| 4 | 58 | 0.36 | 0.78 | 13 | empty |
Interfaces
3 interfaces between chains.
- A–B · 1299 Ų buried · 22 hydrogen bonds · protein-protein
- A–C · 677 Ų buried · 7 hydrogen bonds · protein-protein
- B–C · 435 Ų buried · 5 hydrogen bonds · protein-protein
Compared structures
- 2E4M · Crystal structure of hemagglutinin subcomponent complex (HA-33/HA-17) from Clostridium… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P46084
- Every structure of UniProt Q9LBR4
- Elsewhere: RCSB PDB 2E4M · PDBe 2E4M · UniProt P46084 · UniProt Q9LBR4
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