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Crystal structure of MS0666

Analyse Crystal structure of MS0666 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2DTC
Type: protein
Length: 231 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Ral guanine nucleotide exchange factor RALGPS1A
UniProt: Q8BVR9
Pockets: 1 · best druggability 0.63

Structure

x-ray diffraction · 2 distinct chains · 16% helix, 40% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Ral guanine nucleotide exchange factor RALGPS1A	protein	116	16% helix, 40% strand	Q8BVR9
B	Ral guanine nucleotide exchange factor RALGPS1A	protein	115	16% helix, 40% strand	Q8BVR9

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	194	0.63	0.84	43	empty

Interfaces

1 interface between chains.

A–B · 647 Å² buried · 11 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 4 modified (engineered).

Compared structures

2DTC · Crystal structure of MS0666 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8BVR9
Elsewhere: RCSB PDB 2DTC · PDBe 2DTC · UniProt Q8BVR9

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