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Crystal structure and binding properties of the CD2 and CD244 (2B4) binding protein, CD48

Analyse Crystal structure and binding properties of the CD2 and CD244 (2B4) binding… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2DRU
Type: protein
Length: 180 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Chimera of CD48 antigen and T-cell surface antigen CD2
UniProt: P10252
Ligands: NAG

Structure

x-ray diffraction · 1 distinct chain · 3% helix, 48% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Chimera of CD48 antigen and T-cell surface antigen CD2	protein	180	3% helix, 48% strand	P10252

Ligands and binding sites

NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 3 copies · chains A
GOL · Glycerol · additive · 5 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Modifications

Observed in the structure: 3 glycan, 2 disulfide (N-glycosylation, disulfide).

Compared structures

2DRU · Crystal structure and binding properties of the CD2 and CD244 (2B4) binding protein, CD48 · the same entry in another collection · chain A against A, TM-score 1.00
P10252 · AlphaFold monomer V2.0 prediction for CD48 antigen (P10252) · a predicted model of the same protein · chain A against A, TM-score 0.88

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Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P10252
Elsewhere: RCSB PDB 2DRU · PDBe 2DRU · UniProt P10252

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