Research workbench
Crystal structure of the replication terminator protein mutant RTP.E39K.R42Q
Analyse Crystal structure of the replication terminator protein mutant RTP.E39K.R42Q in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2DQR
- Type
- protein
- Length
- 434 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Replication termination protein
- UniProt
- P68732
- Pockets
- 1 · best druggability 0.50
Structure
x-ray diffraction · 4 distinct chains · 59% helix, 11% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Replication termination protein | protein | 107 | 60% helix, 7% strand | P68732 |
| B | Replication termination protein | protein | 112 | 57% helix, 11% strand | P68732 |
| C | Replication termination protein | protein | 106 | 58% helix, 12% strand | P68732 |
| D | Replication termination protein | protein | 109 | 61% helix, 12% strand | P68732 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 233 | 0.50 | 0.75 | 22 | empty |
Interfaces
4 interfaces between chains.
- A–B · 1574 Ų buried · 20 hydrogen bonds · protein-protein
- C–D · 1531 Ų buried · 12 hydrogen bonds · protein-protein
- A–C · 51 Ų buried · 1 hydrogen bond · protein-protein
- A–D · 51 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 2DQR · Crystal structure of the replication terminator protein mutant RTP.E39K.R42Q · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P68732
- Elsewhere: RCSB PDB 2DQR · PDBe 2DQR · UniProt P68732
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