Research workbench
Crystal structure of TTHA0845 from thermus thermophilus HB8
Analyse Crystal structure of TTHA0845 from thermus thermophilus HB8 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2DJW
- Type
- protein
- Length
- 799 residues
- Chains
- 10
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Probable transcriptional regulator, asnc family
- UniProt
- Q5SK07
- Ligands
- ZN
- Pockets
- 7 · best druggability 0.44
Structure
x-ray diffraction · 2 distinct chains · 26% helix, 44% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D, E, F, G, I, J | Probable transcriptional regulator, asnc family | protein | 80 | 29% helix, 44% strand | Q5SK07 |
| H | Probable transcriptional regulator, asnc family | protein | 79 | 23% helix, 44% strand | Q5SK07 |
Ligands and binding sites
- ZN · Zinc ion · metal · 4 copies · chains B, E, G, J
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
7 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 55 | 0.44 | 0.84 | 18 | empty |
| 2 | 119 | 0.43 | 0.77 | 22 | empty |
| 3 | 63 | 0.42 | 0.82 | 17 | empty |
| 4 | 75 | 0.38 | 0.78 | 19 | empty |
| 5 | 76 | 0.35 | 0.76 | 15 | empty |
Interfaces
25 interfaces between chains.
- D–I · 1456 Ų buried · 29 hydrogen bonds · protein-protein
- A–F · 1423 Ų buried · 26 hydrogen bonds · protein-protein
- E–J · 1415 Ų buried · 25 hydrogen bonds · protein-protein
- B–G · 1405 Ų buried · 22 hydrogen bonds · protein-protein
- C–H · 1368 Ų buried · 23 hydrogen bonds · protein-protein
Compared structures
- 2DJW · Crystal structure of TTHA0845 from Thermus thermophilus HB8 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q5SK07
- Elsewhere: RCSB PDB 2DJW · PDBe 2DJW · UniProt Q5SK07
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.