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Solution structure of the ring domain of the human polycomb group ring finger protein 6

Analyse Solution structure of the ring domain of the human polycomb group ring finger… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
2DJB
Type
protein
Length
72 residues
Chains
1
Method
solution nmr
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Polycomb group ring finger protein 6
UniProt
Q9BYE7
Ligands
ZN
Pockets
1 · best druggability 0.31

Structure

solution nmr · 1 distinct chain · 18% helix, 6% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
APolycomb group ring finger protein 6protein7218% helix, 6% strandQ9BYE7

Ligands and binding sites

  • ZN · Zinc ion · metal · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1580.310.7512empty

Compared structures

  • 2DJB · Solution structure of the RING domain of the human Polycomb group RING finger protein 6 · the same entry in another collection · chain A against A, TM-score 1.00
  • Q9BYE7 · AlphaFold monomer V2.0 prediction for polycomb group ring finger protein 6 (Q9BYE7) · a predicted model of the same protein · chain A against A, TM-score 0.68

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