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Solution structure of nucleic acid binding protein CUGBP1AB and its binding study with DNA and RNA

Analyse Solution structure of nucleic acid binding protein CUGBP1AB and its binding… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
2DHS
Type
protein
Length
187 residues
Chains
1
Method
solution nmr
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Cug triplet repeat RNA-binding protein 1
UniProt
Q92879
Pockets
3 · best druggability 0.39

Structure

solution nmr · 1 distinct chain · 25% helix, 25% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ACug triplet repeat RNA-binding protein 1protein18725% helix, 25% strandQ92879

Pockets

3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1660.390.7815empty
2620.370.7815empty
31090.370.7425empty

Compared structures

  • 2DHS · Solution Structure of Nucleic Acid Binding Protein CUGBP1ab and its Binding Study with… · the same entry in another collection · chain A against A, TM-score 1.00
  • Q92879 · AlphaFold monomer V2.0 prediction for cugbp elav-like family member 1 (Q92879) · a predicted model of the same protein · chain A against A, TM-score 0.49

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