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Solution structure of the thap domain of the human thap domain- containing protein 2

Analyse Solution structure of the thap domain of the human thap domain- containing… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2D8R
Type: protein
Length: 99 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Thap domain-containing protein 2
UniProt: Q9H0W7
Ligands: ZN
Pockets: 1 · best druggability 0.36

Structure

solution nmr · 1 distinct chain · 10% helix, 6% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Thap domain-containing protein 2	protein	99	10% helix, 6% strand	Q9H0W7

Ligands and binding sites

ZN · Zinc ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	72	0.36	0.77	15	empty

Compared structures

2D8R · Solution structure of the thap domain of the human thap domain-containing protein 2 · the same entry in another collection · chain A against A, TM-score 1.00
Q9H0W7 · AlphaFold monomer V2.0 prediction for thap domain-containing protein 2 (Q9H0W7) · a predicted model of the same protein · chain A against A, TM-score 0.73

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9H0W7
Elsewhere: RCSB PDB 2D8R · PDBe 2D8R · UniProt Q9H0W7

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