Research workbench
Structure of chorismate mutase (form I) from thermus thermophilus HB8
Analyse Structure of chorismate mutase (form I) from thermus thermophilus HB8 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2D8D
- Type
- protein
- Length
- 163 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Phospho-2-dehydro-3-deoxyheptonate ALDOLASE/CHORISMATE mutase
- EC
- 5.4.99.5
- UniProt
- Q72LN8
- Ligands
- CL
- Pockets
- 2 · best druggability 0.72
Structure
x-ray diffraction · 2 distinct chains · 82% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Phospho-2-dehydro-3-deoxyheptonate ALDOLASE/CHORISMATE mutase (EC 5.4.99.5) | protein | 80 | 81% helix, 0% strand | Q72LN8 |
| B | Phospho-2-dehydro-3-deoxyheptonate ALDOLASE/CHORISMATE mutase (EC 5.4.99.5) | protein | 83 | 83% helix, 0% strand | Q72LN8 |
Ligands and binding sites
- CL · Chloride ion · ion · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 88 | 0.72 | 0.95 | 15 | empty |
| 2 | 138 | 0.65 | 0.87 | 18 | CL |
Interfaces
1 interface between chains.
- A–B · 2591 Ų buried · 24 hydrogen bonds · protein-protein
Compared structures
- 2D8D · Structure of Chorismate Mutase (Form I) from Thermus Thermophilus HB8 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q72LN8
- Elsewhere: RCSB PDB 2D8D · PDBe 2D8D · UniProt Q72LN8
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