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Crystal structure of the helicase domain of the gene 4 protein of bacteriophage T7: complex with datp

Analyse Crystal structure of the helicase domain of the gene 4 protein of bacteriophage… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1CR2
Type: protein
Length: 239 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: DNA PRIMASE/HELICASE
EC: 2.7.7.-
UniProt: P03692
Ligands: DTP, SO4
Pockets: 2 · best druggability 0.54

Structure

x-ray diffraction · 1 distinct chain · 41% helix, 24% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	DNA PRIMASE/HELICASE (EC 2.7.7.-)	protein	239	41% helix, 24% strand	P03692

Ligands and binding sites

DTP · 2'-deoxyadenosine 5'-triphosphate · ligand · chains A
SO4 · Sulfate ion · ion · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	197	0.54	0.79	32	SO4, DTP
2	95	0.42	0.77	17	empty

Compared structures

1CR2 · Crystal structure of the helicase domain of the gene 4 protein of bacteriophage T7… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P03692
Elsewhere: RCSB PDB 1CR2 · PDBe 1CR2 · UniProt P03692

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