Research workbench

Lipocalin-type prostaglandin D synthase

Analyse Lipocalin-type prostaglandin D synthase in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2CZT
Type: protein
Length: 155 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Prostaglandin-H2 D-isomerase
EC: 5.3.99.2
UniProt: O09114
Pockets: 2 · best druggability 0.79

Structure

x-ray diffraction · 1 distinct chain · 15% helix, 41% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Prostaglandin-H2 D-isomerase (EC 5.3.99.2)	protein	155	15% helix, 41% strand	O09114

Pockets

2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	402	0.79	0.88	42	empty
2	72	0.74	0.97	17	empty

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

2CZT · lipocalin-type prostaglandin D synthase · the same entry in another collection · chain A against A, TM-score 1.00
O09114 · AlphaFold monomer V2.0 prediction for prostaglandin-H2 D-isomerase (O09114) · a predicted model of the same protein · chain A against A, TM-score 0.96

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O09114
Elsewhere: RCSB PDB 2CZT · PDBe 2CZT · UniProt O09114

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.