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Crystal structure of LEUCYL/PHENYLALANYL-tRNA protein transferase from escherichia COLI

Analyse Crystal structure of LEUCYL/PHENYLALANYL-tRNA protein transferase from… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2CXA
Type: protein
Length: 229 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: LEUCYL/PHENYLALANYL-tRNA-protein transferase
EC: 2.3.2.6
UniProt: P0A8P1
Pockets: 2 · best druggability 0.62

Structure

x-ray diffraction · 1 distinct chain · 33% helix, 26% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	LEUCYL/PHENYLALANYL-tRNA-protein transferase (EC 2.3.2.6)	protein	229	33% helix, 26% strand	P0A8P1

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	236	0.62	0.81	30	empty
2	67	0.30	0.74	15	empty

Modifications

Observed in the structure: 8 modified (engineered).

Compared structures

2CXA · Crystal structure of Leucyl/phenylalanyl-tRNA protein transferase from Escherichia coli · the same entry in another collection · chain A against A, TM-score 1.00
P0A8P1 · AlphaFold monomer V2.0 prediction for LEUCYL/PHENYLALANYL-tRNA-- protein transferase… · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P0A8P1
Elsewhere: RCSB PDB 2CXA · PDBe 2CXA · UniProt P0A8P1

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