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Crystal structure of the radb recombinase

Analyse Crystal structure of the radb recombinase in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2CVH
Type: protein
Length: 440 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: DNA repair and recombination protein radb
UniProt: P95547
Pockets: 5 · best druggability 0.73

Structure

x-ray diffraction · 1 distinct chain · 33% helix, 25% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	DNA repair and recombination protein radb	protein	220	33% helix, 25% strand	P95547

Pockets

5 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	193	0.73	0.90	36	empty
2	331	0.58	0.76	40	empty
3	147	0.57	0.82	19	empty
4	55	0.30	0.76	16	empty
5	58	0.29	0.75	15	empty

Interfaces

1 interface between chains.

A–B · 512 Å² buried · 9 hydrogen bonds · protein-protein

Compared structures

2CVH · Crystal structure of the RadB recombinase · the same entry in another collection · chain A against A, TM-score 1.00
P95547 · AlphaFold monomer V2.0 prediction for DNA repair and recombination protein radb (P95547) · a predicted model of the same protein · chain A against A, TM-score 0.93

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P95547
Elsewhere: RCSB PDB 2CVH · PDBe 2CVH · UniProt P95547

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