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Solution structure of the second cut domain of human SATB2

Analyse Solution structure of the second cut domain of human SATB2 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
2CSF
Type
protein
Length
101 residues
Chains
1
Method
solution nmr
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
DNA-binding protein SATB2
UniProt
Q9UPW6
Pockets
1 · best druggability 0.36

Structure

solution nmr · 1 distinct chain · 55% helix, 0% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ADNA-binding protein SATB2protein10155% helix, 0% strandQ9UPW6

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
1960.360.7516empty

Compared structures

  • 2CSF · Solution structure of the second CUT domain of human SATB2 · the same entry in another collection · chain A against A, TM-score 1.00
  • Q9UPW6 · AlphaFold monomer V2.0 prediction for DNA-binding protein SATB2 (Q9UPW6) · a predicted model of the same protein · chain A against A, TM-score 0.79

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