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Solution structure of the RNA recognition motif of CNOT4

Analyse Solution structure of the RNA recognition motif of CNOT4 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2CPI
Type: protein
Length: 111 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: CCR4-not transcription complex subunit 4
EC: 6.3.2.-
UniProt: Q8BT14
Pockets: 1 · best druggability 0.39

Structure

solution nmr · 1 distinct chain · 14% helix, 26% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	CCR4-not transcription complex subunit 4 (EC 6.3.2.-)	protein	111	14% helix, 26% strand	Q8BT14

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	68	0.39	0.78	13	empty

Compared structures

2CPI · Solution structure of the RNA recognition motif of CNOT4 · the same entry in another collection · chain A against A, TM-score 1.00
Q8BT14 · AlphaFold monomer V2.0 prediction for CCR4-not transcription complex subunit 4 (Q8BT14) · a predicted model of the same protein · chain A against A, TM-score 0.71

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8BT14
Elsewhere: RCSB PDB 2CPI · PDBe 2CPI · UniProt Q8BT14

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