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Crystal structure of human cytosolic 5'-nucleotidase III ( NT5C3)(CASP target)

Analyse Crystal structure of human cytosolic 5'-nucleotidase III ( NT5C3)(CASP target) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2CN1
Type: protein
Length: 273 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Cytosolic 5'-nucleotidase III
EC: 3.1.3.5
UniProt: Q9H0P0
Pockets: 1 · best druggability 0.79

Structure

x-ray diffraction · 1 distinct chain · 46% helix, 20% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Cytosolic 5'-nucleotidase III (EC 3.1.3.5)	protein	273	46% helix, 20% strand	Q9H0P0

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	510	0.79	0.86	43	empty

Compared structures

2CN1 · Crystal structure of Human Cytosolic 5'-Nucleotidase III (NT5C3) · the same entry in another collection · chain A against A, TM-score 1.00
Q9H0P0 · AlphaFold monomer V2.0 prediction for cytosolic 5'-nucleotidase 3A (Q9H0P0) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9H0P0
Elsewhere: RCSB PDB 2CN1 · PDBe 2CN1 · UniProt Q9H0P0

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