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Bovine viral diarrhea virus CP7-R12 RNA-dependent RNA polymerase

Analyse Bovine viral diarrhea virus CP7-R12 RNA-dependent RNA polymerase in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
2CJQ
Type
protein
Length
546 residues
Chains
1
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
RNA-directed RNA polymerase
EC
2.7.7.48
UniProt
Q96662
Pockets
5 · best druggability 0.58

Structure

x-ray diffraction · 1 distinct chain · 46% helix, 15% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
ARNA-directed RNA polymerase (EC 2.7.7.48)protein54646% helix, 15% strandQ96662

Pockets

5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
14580.580.7449empty
2870.420.7920empty
3940.400.7721empty
4990.360.7520empty
5840.330.7316empty

Compared structures

  • 2CJQ · Bovine viral diarrhea virus CP7-R12 RNA-dependent RNA polymerase · the same entry in another collection · chain A against A, TM-score 1.00

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