Research workbench
Plant enzyme
Analyse Plant enzyme in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2C7Y
- Type
- protein
- Length
- 787 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- 3-ketoacyl-CoA thiolase 2
- EC
- 2.3.1.16
- UniProt
- Q9S7M3
- Pockets
- 9 · best druggability 0.76
Structure
x-ray diffraction · 2 distinct chains · 38% helix, 23% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 3-ketoacyl-CoA thiolase 2 (EC 2.3.1.16) | protein | 391 | 38% helix, 23% strand | Q9S7M3 |
| B | 3-ketoacyl-CoA thiolase 2 (EC 2.3.1.16) | protein | 396 | 37% helix, 23% strand | Q9S7M3 |
Pockets
9 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 451 | 0.76 | 0.85 | 64 | empty |
| 2 | 359 | 0.71 | 0.84 | 50 | empty |
| 3 | 183 | 0.52 | 0.78 | 18 | empty |
| 4 | 159 | 0.52 | 0.79 | 19 | empty |
| 5 | 66 | 0.42 | 0.81 | 22 | empty |
Interfaces
1 interface between chains.
- A–B · 1291 Ų buried · 18 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 2 disulfide (disulfide).
Compared structures
- 2C7Y · plant enzyme · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9S7M3
- Elsewhere: RCSB PDB 2C7Y · PDBe 2C7Y · UniProt Q9S7M3
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