Research workbench

Crystal structure of chitinase at 1.91A resolution

Analyse Crystal structure of chitinase at 1.91A resolution in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1CNS
Type: protein
Length: 486 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Chitinase
EC: 3.2.1.14
UniProt: P23951
Pockets: 3 · best druggability 0.57

Structure

x-ray diffraction · 1 distinct chain · 46% helix, 2% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Chitinase (EC 3.2.1.14)	protein	243	46% helix, 2% strand	P23951

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	243	0.57	0.79	28	empty
2	155	0.45	0.76	23	empty
3	122	0.41	0.76	23	empty

Interfaces

1 interface between chains.

A–B · 388 Å² buried · 2 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 6 disulfide (disulfide).

Compared structures

1CNS · Crystal structure of chitinase at 1.91A resolution · the same entry in another collection · chain A against A, TM-score 1.00
P23951 · AlphaFold monomer V2.0 prediction for 26 kda endochitinase 2 (P23951) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P23951
Elsewhere: RCSB PDB 1CNS · PDBe 1CNS · UniProt P23951

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.