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The bovine mitochondrial ADP-ATP carrier

Analyse The bovine mitochondrial ADP-ATP carrier in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2C3E
Type: protein
Length: 293 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: ADP/ATP translocase 1
UniProt: P02722
Ligands: CDL, CXT
Pockets: 2 · best druggability 0.74

Structure

x-ray diffraction · 1 distinct chain · 72% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	ADP/ATP translocase 1	protein	293	72% helix, 0% strand	P02722

Ligands and binding sites

CDL · Cardiolipin · ligand · 3 copies · chains A
CXT · Carboxyatractyloside · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	801	0.74	0.79	55	CXT
2	83	0.36	0.76	14	empty

Compared structures

2C3E · The bovine mitochondrial ADP-ATP carrier · the same entry in another collection · chain A against A, TM-score 1.00
P02722 · AlphaFold monomer V2.0 prediction for ADP/ATP translocase 1 (P02722) · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P02722
Elsewhere: RCSB PDB 2C3E · PDBe 2C3E · UniProt P02722

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