Research workbench
14-3-3 protein zeta bound to R18 peptide
Analyse 14-3-3 protein zeta bound to R18 peptide in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1A38
- Type
- protein
- Length
- 442 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- 14-3-3 protein zeta; R18 peptide (phcvprdlswldleanmclp)
- UniProt
- P63103
- Pockets
- 6 · best druggability 0.51
Structure
x-ray diffraction · 2 distinct chains · 80% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | 14-3-3 protein zeta | protein | 216 | 82% helix, 0% strand | P63103 |
| P, Q | R18 peptide (phcvprdlswldleanmclp) | protein | 5 | 0% helix, 0% strand | — |
Pockets
6 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 268 | 0.51 | 0.75 | 26 | empty |
| 2 | 92 | 0.48 | 0.81 | 18 | empty |
| 3 | 86 | 0.44 | 0.80 | 18 | empty |
| 4 | 70 | 0.35 | 0.77 | 17 | empty |
| 5 | 57 | 0.34 | 0.78 | 18 | empty |
Interfaces
3 interfaces between chains.
- A–B · 954 Ų buried · 16 hydrogen bonds · protein-protein
- A–P · 505 Ų buried · 4 hydrogen bonds · protein-protein
- B–Q · 505 Ų buried · 4 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P63103
- Elsewhere: RCSB PDB 1A38 · PDBe 1A38 · UniProt P63103
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.