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Crystal structure of the human retinitis pigmentosa protein 2 (RP2)

Analyse Crystal structure of the human retinitis pigmentosa protein 2 (RP2) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2BX6
Type: protein
Length: 311 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: XRP2 protein
UniProt: O75695
Ligands: SO4
Pockets: 3 · best druggability 0.48

Structure

x-ray diffraction · 1 distinct chain · 25% helix, 33% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	XRP2 protein	protein	311	25% helix, 33% strand	O75695

Ligands and binding sites

SO4 · Sulfate ion · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	151	0.48	0.77	28	empty
2	93	0.39	0.77	28	empty
3	51	0.26	0.73	12	empty

Compared structures

2BX6 · Crystal Structure of the human Retinitis Pigmentosa protein 2 (RP2) · the same entry in another collection · chain A against A, TM-score 1.00
O75695 · AlphaFold monomer V2.0 prediction for protein XRP2 (O75695) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O75695
Elsewhere: RCSB PDB 2BX6 · PDBe 2BX6 · UniProt O75695

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