Research workbench
Three dimensional crystal structures of E. COLI met repressor with and without corepressor
Analyse Three dimensional crystal structures of E. COLI met repressor with and without… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1CMC
- Type
- protein
- Length
- 208 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Met repressor
- UniProt
- P0A8U6
- Ligands
- SAM, MG
- Pockets
- 2 · best druggability 0.45
Structure
x-ray diffraction · 1 distinct chain · 41% helix, 14% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Met repressor | protein | 104 | 41% helix, 14% strand | P0A8U6 |
Ligands and binding sites
- SAM · S-adenosylmethionine · ligand · 2 copies · chains A, B
- MG · Magnesium ion · metal · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 63 | 0.45 | 0.83 | 13 | SAM |
| 2 | 57 | 0.40 | 0.81 | 13 | SAM |
Interfaces
1 interface between chains.
- A–B · 1839 Ų buried · 14 hydrogen bonds · protein-protein
Compared structures
- 1CMC · Three dimensional crystal structures of E. COLI met repressor with and without corepressor · the same entry in another collection · chain A against A, TM-score 1.00
- P0A8U6 · AlphaFold monomer V2.0 prediction for met repressor (P0A8U6) · a predicted model of the same protein · chain A against A, TM-score 0.93
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P0A8U6
- Elsewhere: RCSB PDB 1CMC · PDBe 1CMC · UniProt P0A8U6
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.