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Structure of lactococcal bacteriophage P2 receptor binding protein in complex with a llama vhh domain

Analyse Structure of lactococcal bacteriophage P2 receptor binding protein in complex… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
2BSE
Type
protein
Length
687 residues
Chains
6
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
Receptor binding protein; Llama immunoglobulin
UniProt
Q71AW2
Pockets
1 · best druggability 0.82

Structure

x-ray diffraction · 2 distinct chains · 3% helix, 53% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
A, B, CReceptor binding proteinprotein1073% helix, 53% strandQ71AW2
D, E, FLlama immunoglobulinprotein1222% helix, 53% strand—

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
12520.820.9421empty

Interfaces

9 interfaces between chains.

  • B–C · 959 Ų buried · 15 hydrogen bonds · protein-protein
  • A–C · 952 Ų buried · 13 hydrogen bonds · protein-protein
  • A–B · 951 Ų buried · 14 hydrogen bonds · protein-protein
  • C–F · 606 Ų buried · 13 hydrogen bonds · protein-protein
  • B–D · 580 Ų buried · 15 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 3 disulfide (disulfide).

Compared structures

  • 2BSE · Structure of Lactococcal Bacteriophage p2 Receptor Binding Protein in complex with a… · the same entry in another collection · chain A against A, TM-score 1.00

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