Research workbench
Crystal structure of bovine neurophysin II complexed with the vasopressin analogue phe-tyr amide
Analyse Crystal structure of bovine neurophysin II complexed with the vasopressin… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2BN2
- Type
- protein
- Length
- 330 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Neurophysin II
- UniProt
- P01180
- Pockets
- 1 · best druggability 0.35
Structure
x-ray diffraction · 2 distinct chains · 18% helix, 35% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Neurophysin II | protein | 87 | 20% helix, 33% strand | P01180 |
| C, E, G | Neurophysin II | protein | 81 | 17% helix, 37% strand | P01180 |
Pockets
1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 66 | 0.35 | 0.77 | 15 | empty |
Interfaces
3 interfaces between chains.
- E–G · 577 Ų buried · 13 hydrogen bonds · protein-protein
- A–C · 567 Ų buried · 9 hydrogen bonds · protein-protein
- A–E · 357 Ų buried · 3 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 28 disulfide (disulfide).
Compared structures
- 2BN2 · Crystal structure of bovine neurophysin II complexed with the vasopressin analogue… · the same entry in another collection · chain A against A, TM-score 1.00
- P01180 · AlphaFold monomer V2.0 prediction for vasopressin-neurophysin 2-copeptin (P01180) · a predicted model of the same protein · chain C against A, TM-score 0.95
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P01180
- Elsewhere: RCSB PDB 2BN2 · PDBe 2BN2 · UniProt P01180
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.