Research workbench
Mycobacterium tuberculosis epsp synthase in unliganded state
Analyse Mycobacterium tuberculosis epsp synthase in unliganded state in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2BJB
- Type
- protein
- Length
- 421 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- 3-phosphoshikimate 1-carboxyvinyltransferase
- EC
- 2.5.1.19
- UniProt
- P22487
- Ligands
- NA
- Pockets
- 5 · best druggability 0.60
Structure
x-ray diffraction · 1 distinct chain · 36% helix, 23% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 3-phosphoshikimate 1-carboxyvinyltransferase (EC 2.5.1.19) | protein | 421 | 36% helix, 23% strand | P22487 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 443 | 0.60 | 0.75 | 44 | empty |
| 2 | 119 | 0.47 | 0.79 | 19 | empty |
| 3 | 55 | 0.32 | 0.77 | 21 | empty |
| 4 | 55 | 0.32 | 0.76 | 18 | empty |
| 5 | 55 | 0.26 | 0.73 | 15 | empty |
Compared structures
- 2BJB · Mycobacterium Tuberculosis Epsp Synthase In Unliganded State · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P22487
- Elsewhere: RCSB PDB 2BJB · PDBe 2BJB · UniProt P22487
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