Research workbench
Structure of mRNA capping enzyme in complex with the cap analog gpppg
Analyse Structure of mRNA capping enzyme in complex with the cap analog gpppg in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1CKO
- Type
- protein
- Length
- 317 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- MRNA capping enzyme
- EC
- 2.7.7.50
- UniProt
- Q84424
- Ligands
- GP3, ZN
- Pockets
- 1 · best druggability 0.64
Structure
x-ray diffraction · 1 distinct chain · 21% helix, 41% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | MRNA capping enzyme (EC 2.7.7.50) | protein | 317 | 21% helix, 41% strand | Q84424 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 460 | 0.64 | 0.77 | 51 | GP3 |
Compared structures
- 1CKO · Structure of mRNA capping enzyme in complex with the cap analog gpppg · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q84424
- Elsewhere: RCSB PDB 1CKO · PDBe 1CKO · UniProt Q84424
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