Research workbench

Solution structure of human sulfiredoxin (srx)

Analyse Solution structure of human sulfiredoxin (srx) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2B6F
Type: protein
Length: 121 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Sulfiredoxin
EC: 1.18.-.-
UniProt: Q9BYN0
Ligands: ATP, MG
Pockets: 1 · best druggability 0.30

Structure

solution nmr · 1 distinct chain · 27% helix, 22% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Sulfiredoxin (EC 1.18.-.-)	protein	121	27% helix, 22% strand	Q9BYN0

Ligands and binding sites

ATP · Adenosine-5'-triphosphate · ligand · chains A
MG · Magnesium ion · metal

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	53	0.30	0.76	14	empty

Modifications

Observed in the structure: 1 covalent (covalent ligand).

Compared structures

2B6F · Solution structure of human sulfiredoxin (SRX) · the same entry in another collection · chain A against A, TM-score 1.00
Q9BYN0 · AlphaFold monomer V2.0 prediction for sulfiredoxin-1 (Q9BYN0) · a predicted model of the same protein · chain A against A, TM-score 0.79

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9BYN0
Elsewhere: RCSB PDB 2B6F · PDBe 2B6F · UniProt Q9BYN0

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