Research workbench

Crystal structure of the beta subunit from DNA polymerase of streptococcus pyogenes

Analyse Crystal structure of the beta subunit from DNA polymerase of streptococcus… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2AVT
Type: protein
Length: 743 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: DNA polymerase III beta subunit
EC: 2.7.7.-
Pockets: 9 · best druggability 0.73

Structure

x-ray diffraction · 2 distinct chains · 23% helix, 43% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	DNA polymerase III beta subunit (EC 2.7.7.-)	protein	372	23% helix, 43% strand	—
B	DNA polymerase III beta subunit (EC 2.7.7.-)	protein	371	22% helix, 43% strand	—

Pockets

9 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	53	0.73	0.98	19	empty
2	102	0.40	0.77	24	empty
3	94	0.40	0.77	22	empty
4	102	0.38	0.75	18	empty
5	59	0.37	0.79	18	empty

Interfaces

1 interface between chains.

A–B · 1142 Å² buried · 22 hydrogen bonds · protein-protein

Compared structures

2AVT · Crystal structure of the beta subunit from DNA polymerase of Streptococcus pyogenes · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 2AVT · PDBe 2AVT

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.