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Structural and functional analysis of ADA2 alpha swirm domain

Analyse Structural and functional analysis of ADA2 alpha swirm domain in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2AQE
Type: protein
Length: 90 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Transcriptional adaptor 2, ADA2 alpha
UniProt: Q8BNK0
Pockets: 1 · best druggability 0.36

Structure

solution nmr · 1 distinct chain · 49% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Transcriptional adaptor 2, ADA2 alpha	protein	90	49% helix, 0% strand	Q8BNK0

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	69	0.36	0.78	16	empty

Compared structures

2AQE · Structural and functional analysis of ada2 alpha swirm domain · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8BNK0
Elsewhere: RCSB PDB 2AQE · PDBe 2AQE · UniProt Q8BNK0

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