Research workbench
Cyrstal structure of cocaine catalytic antibody 7A1 Fab'
Analyse Cyrstal structure of cocaine catalytic antibody 7A1 Fab' in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2AJU
- Type
- protein
- Length
- 435 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Antibody 7A1 Fab'
- Pockets
- 5 · best druggability 0.59
Structure
x-ray diffraction · 2 distinct chains · 6% helix, 50% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| L | Antibody 7A1 Fab' | protein | 216 | 6% helix, 49% strand | — |
| H | Antibody 7A1 Fab' | protein | 219 | 7% helix, 51% strand | — |
Pockets
5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 459 | 0.59 | 0.75 | 52 | empty |
| 2 | 238 | 0.56 | 0.78 | 28 | empty |
| 3 | 154 | 0.48 | 0.77 | 18 | empty |
| 4 | 66 | 0.45 | 0.83 | 23 | empty |
| 5 | 71 | 0.32 | 0.75 | 15 | empty |
Interfaces
1 interface between chains.
- L–H · 1909 Ų buried · 16 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 4 disulfide (disulfide).
Compared structures
- 2AJU · Cyrstal structure of cocaine catalytic antibody 7A1 Fab' · the same entry in another collection · chain L against L, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 2AJU · PDBe 2AJU
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.