Research workbench
X-ray structure of a putative adenylate cyclase Q87NV8 from vibrio parahaemolyticus at the 2.25 a resolution. northeast structural genomics target VPR19.
Analyse X-ray structure of a putative adenylate cyclase Q87NV8 from vibrio… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2ACA
- Type
- protein
- Length
- 348 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Putative adenylate cyclase
- UniProt
- Q87NV8
- Ligands
- PO4
- Pockets
- 3 · best druggability 0.76
Structure
x-ray diffraction · 1 distinct chain · 23% helix, 46% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Putative adenylate cyclase | protein | 174 | 23% helix, 46% strand | Q87NV8 |
Ligands and binding sites
- PO4 · Phosphate ion · ion · 5 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 633 | 0.76 | 0.82 | 63 | PO4 |
| 2 | 651 | 0.72 | 0.79 | 57 | PO4 |
| 3 | 57 | 0.29 | 0.75 | 23 | empty |
Interfaces
1 interface between chains.
- A–B · 1114 Ų buried · 22 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 10 modified (engineered).
Compared structures
- 2ACA · X-ray structure of a putative adenylate cyclase Q87NV8 from Vibrio parahaemolyticus at… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q87NV8
- Elsewhere: RCSB PDB 2ACA · PDBe 2ACA · UniProt Q87NV8
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.