Research workbench
Deoxyribose-phosphate aldolase from P. yoelii
Analyse Deoxyribose-phosphate aldolase from P. yoelii in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 2A4A
- Type
- protein
- Length
- 497 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Deoxyribose-phosphate aldolase
- EC
- 4.1.2.4
- UniProt
- Q7RMC9
- Pockets
- 6 · best druggability 0.67
Structure
x-ray diffraction · 2 distinct chains · 53% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Deoxyribose-phosphate aldolase (EC 4.1.2.4) | protein | 250 | 53% helix, 15% strand | Q7RMC9 |
| B | Deoxyribose-phosphate aldolase (EC 4.1.2.4) | protein | 247 | 53% helix, 15% strand | Q7RMC9 |
Pockets
6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 563 | 0.67 | 0.77 | 52 | empty |
| 2 | 280 | 0.56 | 0.76 | 38 | empty |
| 3 | 117 | 0.46 | 0.79 | 27 | empty |
| 4 | 101 | 0.45 | 0.80 | 19 | empty |
| 5 | 105 | 0.40 | 0.76 | 22 | empty |
Interfaces
1 interface between chains.
- A–B · 396 Ų buried · 9 hydrogen bonds · protein-protein
Compared structures
- 2A4A · Deoxyribose-phosphate aldolase from P. yoelii · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q7RMC9
- Elsewhere: RCSB PDB 2A4A · PDBe 2A4A · UniProt Q7RMC9
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