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1.5 a crystal structure of a protein of unknown function PA4017 from pseudomonas aeruginosa PAO1, possible epimerase

Analyse 1.5 a crystal structure of a protein of unknown function PA4017 from… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 2A35
Type: protein
Length: 416 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Hypothetical protein PA4017
UniProt: Q9HX10
Pockets: 5 · best druggability 0.66

Structure

x-ray diffraction · 2 distinct chains · 43% helix, 18% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Hypothetical protein PA4017	protein	208	42% helix, 18% strand	Q9HX10
B	Hypothetical protein PA4017	protein	208	43% helix, 19% strand	Q9HX10

Pockets

5 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	294	0.66	0.82	32	empty
2	316	0.62	0.79	36	empty
3	89	0.52	0.83	19	empty
4	143	0.48	0.78	23	empty
5	171	0.46	0.75	42	empty

Interfaces

1 interface between chains.

A–B · 844 Å² buried · 10 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

2A35 · 1.5 A Crystal Structure of a Protein of Unknown Function PA4017 from Pseudomonas… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9HX10
Elsewhere: RCSB PDB 2A35 · PDBe 2A35 · UniProt Q9HX10

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