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Crystal structure of hypothetical protein TT0462 from thermus thermophilus HB8

Analyse Crystal structure of hypothetical protein TT0462 from thermus thermophilus HB8 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1ZZG
Type: protein
Length: 830 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Glucose-6-phosphate isomerase
EC: 5.3.1.9
UniProt: Q5SLL6
Pockets: 6 · best druggability 0.82

Structure

x-ray diffraction · 1 distinct chain · 53% helix, 15% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Glucose-6-phosphate isomerase (EC 5.3.1.9)	protein	415	53% helix, 15% strand	Q5SLL6

Pockets

6 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1033	0.82	0.83	80	empty
2	307	0.65	0.81	49	empty
3	203	0.61	0.82	26	empty
4	51	0.37	0.80	13	empty
5	86	0.36	0.76	14	empty

Interfaces

1 interface between chains.

A–B · 5065 Å² buried · 57 hydrogen bonds · protein-protein

Compared structures

1ZZG · Crystal structure of hypothetical protein TT0462 from Thermus thermophilus HB8 · the same entry in another collection · chain A against A, TM-score 1.00
Q5SLL6 · AlphaFold monomer V2.0 prediction for glucose-6-phosphate isomerase (Q5SLL6) · a predicted model of the same protein · chain B against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q5SLL6
Elsewhere: RCSB PDB 1ZZG · PDBe 1ZZG · UniProt Q5SLL6

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