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Solution structure of icln, a multifunctional protein involved in regulatory mechanisms as different as cell volume regulation and RNA splicing

Analyse Solution structure of icln, a multifunctional protein involved in regulatory… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1ZYI
Type: protein
Length: 116 residues
Chains: 1
Method: solution nmr
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Methylosome subunit picln
UniProt: P35521
Pockets: 1 · best druggability 0.68

Structure

solution nmr · 1 distinct chain · 14% helix, 36% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Methylosome subunit picln	protein	116	14% helix, 36% strand	P35521

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	175	0.68	0.86	25	empty

Compared structures

1ZYI · Solution structure of ICLN, a multifunctional protein involved in regulatory mechanisms… · the same entry in another collection · chain A against A, TM-score 1.00
P35521 · AlphaFold monomer V2.0 prediction for methylosome subunit picln (P35521) · a predicted model of the same protein · chain A against A, TM-score 0.60

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P35521
Elsewhere: RCSB PDB 1ZYI · PDBe 1ZYI · UniProt P35521

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