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Crystal structure of the carboxyl terminal pH domain of pleckstrin to 2.1 ångströms

Analyse Crystal structure of the carboxyl terminal pH domain of pleckstrin to 2.1… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1ZM0
Type: protein
Length: 194 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Pleckstrin
UniProt: P08567
Pockets: 1 · best druggability 0.57

Structure

x-ray diffraction · 2 distinct chains · 14% helix, 44% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Pleckstrin	protein	96	15% helix, 45% strand	P08567
B	Pleckstrin	protein	98	14% helix, 44% strand	P08567

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	55	0.57	0.91	19	empty

Interfaces

1 interface between chains.

A–B · 594 Å² buried · 7 hydrogen bonds · protein-protein

Compared structures

1ZM0 · Crystal Structure of the Carboxyl Terminal PH Domain of Pleckstrin To 2.1 Angstroms · the same entry in another collection · chain A against A, TM-score 1.00
P08567 · AlphaFold monomer V2.0 prediction for pleckstrin (P08567) · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P08567
Elsewhere: RCSB PDB 1ZM0 · PDBe 1ZM0 · UniProt P08567

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