Research workbench

BEF3- activated phob receiver domain

Analyse BEF3- activated phob receiver domain in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1ZES
Type: protein
Length: 359 residues
Chains: 3
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Phosphate regulon transcriptional regulatory protein phob
UniProt: P08402
Ligands: BEF, MG
Pockets: 2 · best druggability 0.44

Structure

x-ray diffraction · 3 distinct chains · 44% helix, 19% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Phosphate regulon transcriptional regulatory protein phob	protein	121	44% helix, 19% strand	P08402
B	Phosphate regulon transcriptional regulatory protein phob	protein	118	44% helix, 19% strand	P08402
C	Phosphate regulon transcriptional regulatory protein phob	protein	120	45% helix, 19% strand	P08402

Ligands and binding sites

BEF · Beryllium trifluoride ion · ligand · 3 copies · chains A, B, C
MG · Magnesium ion · metal · 3 copies · chains A, B, C

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	121	0.44	0.78	18	empty
2	82	0.31	0.73	15	empty

Interfaces

2 interfaces between chains.

B–C · 1043 Å² buried · 26 hydrogen bonds · protein-protein
A–C · 199 Å² buried · 6 hydrogen bonds · protein-protein

Compared structures

1ZES · BeF3- activated PhoB receiver domain · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P08402
Elsewhere: RCSB PDB 1ZES · PDBe 1ZES · UniProt P08402

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.