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Crystal structure of peptide chain release factor 1 (rf-1) (SMU.1085) from streptococcus mutans at 2.34 a resolution

Analyse Crystal structure of peptide chain release factor 1 (rf-1) (SMU.1085) from… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1ZBT
Type: protein
Length: 320 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Peptide chain release factor 1
UniProt: Q8DU64
Pockets: 3 · best druggability 0.60

Structure

x-ray diffraction · 1 distinct chain · 47% helix, 23% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Peptide chain release factor 1	protein	320	47% helix, 23% strand	Q8DU64

Pockets

3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	285	0.60	0.78	34	empty
2	312	0.57	0.76	26	empty
3	57	0.35	0.78	12	empty

Modifications

Observed in the structure: 9 modified (engineered).

Compared structures

1ZBT · Crystal structure of Peptide chain release factor 1 (RF-1) (SMU.1085) from Streptococcus… · the same entry in another collection · chain A against A, TM-score 1.00
Q8DU64 · AlphaFold monomer V2.0 prediction for peptide chain release factor 1 (Q8DU64) · a predicted model of the same protein · chain A against A, TM-score 0.63

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8DU64
Elsewhere: RCSB PDB 1ZBT · PDBe 1ZBT · UniProt Q8DU64

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