Research workbench
Crystal structure of a hypothetical protein TT1821 from thermus thermophilus
Analyse Crystal structure of a hypothetical protein TT1821 from thermus thermophilus in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1Z54
- Type
- protein
- Length
- 522 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Probable thioesterase
- UniProt
- Q5SJV0
- Pockets
- 7 · best druggability 0.88
Structure
x-ray diffraction · 4 distinct chains · 26% helix, 41% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Probable thioesterase | protein | 132 | 26% helix, 40% strand | Q5SJV0 |
| B | Probable thioesterase | protein | 131 | 27% helix, 39% strand | Q5SJV0 |
| C | Probable thioesterase | protein | 129 | 26% helix, 42% strand | Q5SJV0 |
| D | Probable thioesterase | protein | 130 | 25% helix, 43% strand | Q5SJV0 |
Ligands and binding sites
- GOL · Glycerol · additive · 3 copies · chains A, C, D, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
7 pockets found on a 1 Å grid, 7 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 468 | 0.88 | 0.95 | 33 | empty |
| 2 | 209 | 0.70 | 0.86 | 35 | empty |
| 3 | 198 | 0.68 | 0.86 | 32 | GOL |
| 4 | 173 | 0.67 | 0.86 | 30 | empty |
| 5 | 215 | 0.65 | 0.84 | 32 | empty |
Interfaces
6 interfaces between chains.
- B–D · 944 Ų buried · 13 hydrogen bonds · protein-protein
- A–C · 936 Ų buried · 12 hydrogen bonds · protein-protein
- A–D · 835 Ų buried · 9 hydrogen bonds · protein-protein
- B–C · 799 Ų buried · 8 hydrogen bonds · protein-protein
- C–D · 471 Ų buried · 2 hydrogen bonds · protein-protein
Compared structures
- 1Z54 · Crystal structure of a hypothetical protein TT1821 from Thermus thermophilus · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q5SJV0
- Elsewhere: RCSB PDB 1Z54 · PDBe 1Z54 · UniProt Q5SJV0
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.