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Structure of phanerochaete chrysosporium cellobiohydrolase CEL7D (CBH58) in complex with cellobiose

Analyse Structure of phanerochaete chrysosporium cellobiohydrolase CEL7D (CBH58) in… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1Z3T
Type: protein
Length: 431 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Cellulase
EC: 3.2.1.91
UniProt: Q7LIJ0
Ligands: BGC, NAG
Pockets: 2 · best druggability 0.76

Structure

x-ray diffraction · 1 distinct chain · 14% helix, 35% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Cellulase (EC 3.2.1.91)	protein	431	14% helix, 35% strand	Q7LIJ0

Ligands and binding sites

BGC · beta-D-glucopyranose · sugar · 2 copies · chains A
NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	877	0.76	0.80	67	BGC
2	50	0.39	0.82	18	empty

Modifications

Observed in the structure: 8 disulfide, 1 glycan, 1 modified (disulfide, N-glycosylation, cyclization).

Compared structures

1Z3T · Structure of Phanerochaete chrysosporium cellobiohydrolase Cel7D (CBH58) in complex with… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q7LIJ0
Elsewhere: RCSB PDB 1Z3T · PDBe 1Z3T · UniProt Q7LIJ0

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